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You know XIENCE as the world's leading drug-eluting stent (DES), with an unparalleled safety record.1 The XIENCE safety heritage is now further strengthened with XIENCE Sierra’s exceptional acute performance. XIENCE Sierra continues to provide unparalleled safety1 along with enhanced deliverability for even the most complex percutaneous coronary interventions (PCI). Learn more about what XIENCE Sierra offers for even the most complex patients.

The Science Behind XIENCE Sierra

XIENCE Sierra features an ultra-low crossing profile* (0.0390″) that provides excellent deliverability. This newest generation XIENCE stent also offers expanded treatment options: 5.5 mm maximum post expansion.#

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The Science Behind XIENCE Sierra

XIENCE Sierra features an ultra-low crossing profile (0.0390″) that provides excellent deliverability. This newest generation XIENCE stent also offers expanded treatment options: 5.5 mm maximum post expansion.#

more

XIENCE Safety For Complex PCI

Multiple recent XIENCE trial results, with endpoints ranging from 1 to 3 years,4-7 reveal excellent safety data on stent thrombosis (ST) in left main disease, diabetes and other complex conditions.

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Xience Safety For Complex PCI

Multiple recent XIENCE trial results, with endpoints ranging from 1 to 3 years,4-7 reveal excellent safety data on stent thrombosis (ST) in left main disease, diabetes and other complex conditions.

more

Experts' and Patient's point of view

And Now . . . XIENCE Sierra Safety for Complex PCI

“This is a marked improvement. The ability to reach these lesions in complex situations is fantastic with this new XIENCE Sierra product.”

Richard Shlofmitz, MD 

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And Now . . . XIENCE Sierra Safety for Complex PCI

“This is a marked improvement. The ability to reach these lesions in complex situations is fantastic with this new XIENCE Sierra product.”

Richard Shlofmitz, MD 

Play video

And Now . . . XIENCE Sierra Safety for Complex PCI

“This is a marked improvement. The ability to reach these lesions in complex situations is fantastic with this new XIENCE Sierra product.”

Richard Shlofmitz, MD 

Play video

And Now . . . XIENCE Sierra Safety for Complex PCI

“This is a marked improvement. The ability to reach these lesions in complex situations is fantastic with this new XIENCE Sierra product.”

Richard Shlofmitz, MD 

Play video

Get the Latest Data

Sign up to receive the latest about XIENCE study results, as they become available.

AP2944530-WBO Rev. B

 

# Maximum expansion for 3.5 mm and 4.0 mm

Test performed by and data on file at Abbott. XIENCE Sierra Everolimus Eluting Coronary Stent System (3.0 x 18 mm) n=5, SYNERGY Stent System (3.0 x 20 mm) n=5, Resolute Onyx Stent System (3.0 x 18 mm) n=5.

  1. XIENCE showed significant benefit compared to several DES and composite BMS in multiple large scale meta-analyses and other RCTs. Source: Palmerini, et al. The Lancet. 379:9824, 14-20 April 2012, pp. 1393-1402; Bangalore S, et al. Circ Cardiovasc Interv, Aug 6, 2013. doi: 10.1161/ circinterventions.113.000415.; Valgimigli, Effects of Cobalt-chromium Everolimus eluting or bare metal stent on fatal and non-fatal cardiovascular events. A patient-level meta analysis. EuroPCR 2014; Serruys, PW et al. RESOLUTE All Comers Trial, NEJM 2010. Published online June 16, 2010; Fajadet, J., et al. PLATINUM PLUS 30-day Poster, TCT 2012.
  2. Bench test data shows that XIENCE Sierra performed better in crossability and was not statistically different in trackability and pushability compared to Resolute Onyx and SYNERGY stents. Bench test results may not necessarily be indicative of clinical performance. Test performed by and data on file at Abbott. Testing performed on XIENCE Sierra Everolimus Eluting Coronary Stent System (3.0 x 18 mm) n=5, SYNERGY Stent System (3.0 x20 mm) n=5, Resolute Onyx Stent System (3.0 x 18 mm) n=5. Catheter performance crossability test measures average force to cross a challenging lesion model.
  3. Increased maximum expansion compared to other XIENCE Everolimus Eluting Coronary Stent System.
  4. Stone GW, et al. EXCEL Trial 3-year data. N Engl J Med. 2016;375:2223-2235. doi: 10.1056/NEJMoa1610227.
  5. Teeuwen K, et al. PRISON IV Trial 1-year data. JACC Cardiovasc Interv. 2016. doi: 10.1016/ j.jcin.2016.10.017.
  6. Kaul U. 2-Year TUXEDO Outcomes. TCT 2016.
  7. Lam, M. TWENTE Trial. Am Heart J.  2015;169:69-77. doi: 10.1016/j.ahj.2014.10.011.
  8. Palmerini T, et al. Lancet. 2012:379:1393-1402.

 

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