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You know XIENCE as the world's leading drug-eluting stent (DES), with an unparalleled safety record.1 The XIENCE safety heritage is now further strengthened with XIENCE Sierra’s exceptional acute performance. XIENCE Sierra continues to provide unparalleled safety1 along with enhanced deliverability for even the most complex percutaneous coronary interventions (PCI). Learn more about what XIENCE Sierra offers for even the most complex patients.

The Science Behind XIENCE Sierra

XIENCE Sierra features an ultra-low crossing profile* (0.0390″) that provides excellent deliverability. This newest generation XIENCE stent also offers expanded treatment options: 5.5 mm maximum post expansion.#

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The Science Behind XIENCE Sierra

XIENCE Sierra features an ultra-low crossing profile (0.0390″) that provides excellent deliverability. This newest generation XIENCE stent also offers expanded treatment options: 5.5 mm maximum post expansion.#

more

XIENCE Safety For Complex PCI

Xience stent thrombosis rate

Multiple recent XIENCE trial results, with endpoints ranging from 1 to 3 years,4-7 reveal excellent safety data on stent thrombosis (ST) in left main disease, diabetes and other complex conditions.

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Xience Safety For Complex PCI

Xience stent thrombosis rate

Multiple recent XIENCE trial results, with endpoints ranging from 1 to 3 years,4-7 reveal excellent safety data on stent thrombosis (ST) in left main disease, diabetes and other complex conditions.

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Experts' and Patient's point of view

From comparative testing of XIENCE

In testing thromboresistance: “We are finding that circumferential [polymer coatings] behave much better. But by far the best is XIENCE.”

Renu Virmani, MD

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From comparative testing of XIENCE

In testing thromboresistance: “We are finding that circumferential [polymer coatings] behave much better. But by far the best is XIENCE.”

Renu Virmani, MD

Play video

From comparative testing of XIENCE

In testing thromboresistance: “We are finding that circumferential [polymer coatings] behave much better. But by far the best is XIENCE.”

Renu Virmani, MD

Play video

From comparative testing of XIENCE

In testing thromboresistance: “We are finding that circumferential [polymer coatings] behave much better. But by far the best is XIENCE.”

Renu Virmani, MD

Play video

From comparative testing of XIENCE
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From comparative testing of XIENCE
To comparative clinical data
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To comparative
clinical data
To live-saving implants for patients
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To life-saving implants for patients

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References

 

# Maximum expansion for 3.5 mm and 4.0 mm

* Test performed by and data on file at Abbott. XIENCE Sierra Everolimus Eluting Coronary Stent System (3.0 x 18 mm) n=5, SYNERGY Stent System (3.0 x 20 mm) n=5, Resolute Onyx Stent System (3.0 x 18 mm) n=5.

  1. XIENCE showed significant benefit compared to several DES and composite BMS in multiple large scale meta-analyses and other RCTs. Source: Palmerini, et al. The Lancet. 379:9824, 14-20 April 2012, pp. 1393-1402; Bangalore S, et al. Circ Cardiovasc Interv, Aug 6, 2013. doi: 10.1161/ circinterventions.113.000415.; Valgimigli, Effects of Cobalt-chromium Everolimus eluting or bare metal stent on fatal and non-fatal cardiovascular events. A patient-level meta analysis. EuroPCR 2014; Serruys, PW et al. RESOLUTE All Comers Trial, NEJM 2010. Published online June 16, 2010; Fajadet, J., et al. PLATINUM PLUS 30-day Poster, TCT 2012.
  2. Bench test data shows that XIENCE Sierra performed better in crossability and was not statistically different in trackability and pushability compared to Resolute Onyx and SYNERGY stents. Bench test results may not necessarily be indicative of clinical performance. Test performed by and data on file at Abbott. Testing performed on XIENCE Sierra Everolimus Eluting Coronary Stent System (3.0 x 18 mm) n=5, SYNERGY Stent System (3.0 x20 mm) n=5, Resolute Onyx Stent System (3.0 x 18 mm) n=5. Catheter performance crossability test measures average force to cross a challenging lesion model.
  3. Increased maximum expansion compared to other XIENCE Everolimus Eluting Coronary Stent System.
  4. Stone GW, et al. EXCEL Trial 3-year data. N Engl J Med. 2016;375:2223-2235. doi: 10.1056/NEJMoa1610227.
  5. Teeuwen K, et al. PRISON IV Trial 1-year data. JACC Cardiovasc Interv. 2016. doi: 10.1016/ j.jcin.2016.10.017.
  6. Kaul U. 2-Year TUXEDO Outcomes. TCT 2016.
  7. Lam, M. TWENTE Trial. Am Heart J.  2015;169:69-77. doi: 10.1016/j.ahj.2014.10.011.

 

 

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Caution: This product is intended for use by or under the direction of a physician. Prior to use, reference the Instructions for Use provided inside the product carton (when available), at eifu.abbottvascular.com or at Manuals.sjm.com for more detailed information on Indications, Contraindications, Warnings, Precautions and Adverse Events.

Information contained herein for distribution outside the U.S. only. Check the regulatory status of the device before distribution in areas where CE marking is not the regulation in force. 

Tests performed by and data on file at Abbott. Illustrations are artist’s representations only and should not be considered as engineering drawings or photographs. Photos on file at Abbott.


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XIENCE V , XIENCE PRIME,  XIENCE Xpedition, and XIENCE Alpine are trademarks of the Abbott Group of Companies. Promus Element, Promus Element Plus, Promus Premier and Synergy are trademarks of Boston Scientific Corporation or its affiliates. Resolute, Resolute Integrity and Resolute Onyx are trademarks of Medtronic, Inc. Nobori and Ultimaster are trademarks of Terumo Corporation. BioMatrix and BioMatrix Flex are trademarks of Biosensors International. Orsiro is a trademark of Biotronik SE & Co. KG. Cypher is a trademark of Cordis, a Cardinal Health company.

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