XIENCE Sierra: Slim, Strong, Precise

Specifically Designed for the Treatment of Complex Patients

To provide effective treatment in complex lesions during percutaneous coronary intervention (PCI), a stent must be slim so it can get to the lesion, strong to effectively treat challenging vessels, while also offering precise stent placement and deployment. XIENCE Sierra has all three characteristics.

SLIM

owest crossing profile of any drug-eluting stent (DES) on the market1

STRONG

Greatest longitudinal strength of any DES, best stent retention on the market, and robust radial stength2  

PRECISE

100% accurate mid-market placement with 0% shortening for precise stent placement 

Slim: Lowest Crossing Profile

XIENCE Sierra’s Slim Flex Technology is a key innovation: it enables XIENCE Sierra to have the lowest crossing profile of any drug-eluting stent on the U.S. market while enhancing the maximum expansion capability.1 This makes it an ideal choice: 

  • For tight, calcified lesions
  • In small, tapered vessels like those in patients with diabetes
  • For patients best treated via radial access 

SLIM FLEX TECHNOLOGY

XIENCE Alpine
0.0425"

EluNIR
0.0421"

Resolute Onyx
0.0405"

Synergy
0.0393"

XIENCE Sierra
0.0390"

Strong: Longitudinal Strength, Retention, and Radial Strength

GREATEST LONGITUDINAL STRENGTH2

XIENCE Sierra has the greatest longitudinal strength of any drug-eluting stent on the market.2 When tested for stent compression (shortening of the stent under a 50gf load), XIENCE Sierra demonstrates: 

Lower values indicate stronger performance.

BEST STENT RETENTION ON THE MARKET2

In addition, XIENCE Sierra exhibits market-leading stent retention, which is critical in challenging anatomy. In testing stent retention*, data2 show that XIENCE Sierra is:

80%

Stronger Than Synergy

150%

Stronger Than Orsiro

199%

Stronger Than Resolute Onyx

ROBUST RADIAL STRENGTH

XIENCE Sierra radial strength is also robust in comparison to competitors.3 

Radial Strength Average (mmHg) for 3.0 mm Size
XIENCE Sierra

1,195

Synergy

1,251

Orsiro

1,089

XIENCE Alpine

1,037

1,300

1,250

1,200

1,150

1,100

1,050

1,000

Precise: For Precision Stent Placement

Zero Shortening Upon Deployment

XIENCE Sierra demonstrates 0% stent shortening upon deployment at maximum expansion. This enables the precision in stent placement that is especially critical in complex lesions.2   

Average Shortening (%)
Resolute Onyx 1.35 mm shortening

7.5%

Orsiro 0.954 mm shortening

5.3%

Synergy 0.96 mm shortening

4.8%

XIENCE Sierra 0.0 mm shortening

0.0% shortening

10

5

0

100% ACCURATE STENT MARKER PLACEMENT

A key feature for any stent is accurate delivery to the target lesion, and XIENCE Sierra offers 100% accurate stent mid-marker placement so the stent can be precisely aligned with the lesion.2

100% Accurate Mid-Marker to Mid-Marker

Xience
XIENCE Sierra
3.0 x 18 mm
Xience
Resolute Onyx
3.0 x 18 mm
Xience
Synergy
3.0 x 18 mm
Xience
Orsiro
3.0 x 18 mm

AP2945972-WBU Rev. A

*    Retention testing measured by dislodgement (lbf) average. 

  1. Comparative claim refers to major drug-eluting stent manufacturers in U.S. market. Test performed by and data on file at Abbott. Refers to small diameter sizes of 2.25-3.25 mm. XIENCE Sierra Everolimus Eluting Coronary Stent System (3.0 x 18 mm) n=5, Synergy Stent System (3.0 x 20 mm) n=5, Resolute Onyx Stent System (3.0 x 18 mm) n=5. EluNIR Ridaforolimus Eluting Coronary Stent System (Product IFU).
  2. Test performed by and data on file at Abbott. XIENCE Sierra Everolimus Eluting Coronary Stent System (4.0 x 18 mm) n=5, Synergy Stent System (4.0 x 20 mm) n=5, Resolute Onyx Stent System (4.5 x 18 mm) n=5, Orsiro Sirolimus Eluting Coronary Stent System (4.0 x 18 mm) n=5. Orsiro is not available or for sale in the United States as of May 2018. Shortening refers to a 4.0 mm diameter stent deployed to 5.5 mm.
  3. Tests performed by and data on file at Abbott.
  4. Test performed by and data on file at Abbott. Orsiro is not available or for sale in the United States as of May 2018. 

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