There’s a Whole World of Evidence in Support of the XIENCE Stent

The newest generation of XIENCE, XIENCE Sierra, is designed to enhance acute performance and offer users expanded treatment options.

Clinicians have long had confidence in XIENCE, which industry experts consider to be the gold standard. XIENCE is the world's leading drug-eluting stent (DES), with twice as many implants as any other DES.*

Substantial clinical data provide evidence that XIENCE can effectively treat a broad spectrum of patients.


The History of Safe PCI Begins with XIENCE

For over a decade, the XIENCE stent has continued to refine its unique stent design for improved deliverability, healing and proven patient safety. It’s why XIENCE is the most trusted drug-eluting stent.

Given the best in class deliverability and the expanded treatment options‡ of XIENCE Sierra, XIENCE becomes the excellent choice for these complex patients. 

The XIENCE difference results not just from a unique stent design but from a unique fluoropolymer coating. This coating is a key differentiator from other DES, resulting in thromboresistance, minimal inflammatory response and functional healing with XIENCE.1-3

As a result, interventional cardiologists worldwide trust and use XIENCE more than any other stent.

“I think the enhanced deliverability of the XIENCE [Sierra] stent will greatly improve acute performance.”

— Aloke Finn, MD


Peak Performance with XIENCE

XIENCE is effective in a wide range of patients—from simple lesions to complex lesions, and from lower risk individuals to higher risk patients like those with diabetes.

Here are a few of the features that contribute to XIENCE’s quality and performance:

  • Best-in-class deliverability† with the new generation XIENCE Sierra

  • Ultra-low stent crossing profile (0.0390") with XIENCE Sierra
  • XIENCE Sierra's unique design to post dilate to 5.5mm#
  • Flexible and conformable MULTI-LINK design
  • No touching or overlapping struts when crimped 
  • Minimal stent shortening when deployed
  • A catheter optimized for strength, flexibility and pushability 
  • Engineered for complex cases
  • Excellent apposition and complete expansion4,5  

Peak Performance with XIENCE

XIENCE is effective in a wide range of patients—from simple lesions to complex lesions, and from lower risk individuals to higher risk patients like those with diabetes.

Here are a few of the features that contribute to XIENCE’s quality and performance:

  • Best-in-class deliverability with the new generation XIENCE Sierra
  • Ultra-low stent crossing profile (0.0390") with XIENCE Sierra
  • XIENCE Sierra's unique design to post dilate to 5.5mm4
  • Flexible and conformable MULTI-LINK design with all XIENCE stents
  • No touching or overlapping struts when crimped 
  • Minimal stent shortening when deployed
  • A catheter optimized for strength, flexibility and pushability 
  • Engineered for complex percutaneous coronary intervention
  • Excellent apposition and complete expansion5,6  

“From all the data today, every study that's been published, we've seen the lowest rates of both early and late stent thrombosis with fluoropolymer-coated everolimus-eluting stents [XIENCE]. . . . And the best safety profile to date is with fluoropolymer-based devices.” (TCTMD sponsored webcast, 2016)

— Gregg Stone, MD


Ordering Options for XIENCE

XIENCE offers a wide range of sizes for the full spectrum of patient needs. Learn about ordering options for XIENCE Sierra as well as ordering options for XIENCE Alpine

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    *10,000,000 implants number is based on data of DES implants through Q1 2017. Comparative claim based on unit usage in U.S., Japan, China, India, top 5 Western Europe, and Korea. Other leading DES: BSX stents (Promus Element, Promus Element Plus, Promus Premier, Synergy); MDT stents (Resolute, Resolute Integrity, Resolute Onyx); Terumo stents (Nobori, Ultimaster); Biotronik stent (Orsiro); and Biosensors stent (BioMatrix). Data on file at Abbott Vascular.


    † Bench test data shows that XIENCE Sierra performed better in crossability and was not statistically different in trackability and pushability compared to Resolute Onyx and SYNERGY stents. Bench test results may not necessarily be indicative of clinical performance. Test performed by and data on file at Abbott. Testing performed on XIENCE Sierra Everolimus Eluting Coronary Stent System (3.0 x 18 mm) n=5, SYNERGY Stent System (3.0 x 20 mm) n=5, Resolute Onyx Stent System (3.0 x 18 mm) n=5. Catheter performance crossability test measures average force to cross a challenging lesion model.


    ‡ Increased maximum expansion compared to other XIENCE Everolimus Eluting Coronary Stent System.

    # Maximum expansion for 3.5 mm and 4.0 mm

    1. Test performed by and data on file at Abbott. XIENCE Sierra Everolimus Eluting Coronary Stent System (3.0 x 18 mm)
n=5, SYNERGY Stent System (3.0 x 20 mm) n=5, Resolute Onyx Stent System (3.0 x 18 mm) n=5.

    2. Garfinkle AM, et al. Trans Am Soc Artif Intern Organs. 1984;30:432-439.

    3. Otsuka F, et al. JACC Cardiovasc Interv. 2015;8:1248-1260. doi: 10.1016/j.jcin.2015.03.029.
    4. Panchalingam V, et al. ASAIO J. 1993;39:M305-M309.

    5. Kolandaivelu K, et al. Circulation. 2011;123:1400-1409. doi: doi.org/10.1161/CIRCULATIONAHA.110.003210.


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